This is my second true attempt at medical illustration. My first attempt was done in Flash. I drew it out in pencil first, then added color using marker. I have a set that has been with me in one way, shape or form for about 33 years. I started collecting markers since the 6th grade. Then, I went back over it in pencil, using the shading technique and a smudge tool – the real kind of tool and not the photoshop version.